Obesity Pill That Re-Wires Brain Into Feeling Full

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overweightmanFrom Your Health Journal…..”An interesting article from the Times of India entitled Soon, obesity pill that re-wires brain into feeling full. Scientists have gotten closer to developing a diet pill that can prevent obesity by “re-wiring” appetite control in the brain. A recent study has identified a population of stem cells capable of generating new appetite-regulating neurons in the brains of young and adult rodents. Scientists investigated the hypothalamus section of the brain – which regulates sleep and wake cycles, energy expenditure, appetite, thirst, hormone release and many other critical biological functions. The study looked specifically at the nerve cells that regulate appetite. This entire investigation could lead to many positive results in people who have a hard time reducing their calorie intake. In a day and age where obesity is causing people to become ill, and the worries about the rise in the cost of healthcare, this could lead to something positive. Let’s watch this closely to see how it turns out, and if it is entirely safe for humans. Please visit the Times of India web site (link provided below) to read the complete article. The Times of India is an excellent publication with many quality health articles.”

From the article…..

No more toiling hard in the gym to shed flab!

Scientists have inched closer to developing a new diet pill that can prevent obesity by “re-wiring” appetite control in the brain.

A new study, published in the Journal of Neuroscience, has identified a population of stem cells capable of generating new appetite-regulating neurons in the brains of young and adult rodents.

The discovery by researchers at the University of East Anglia (UEA) could offer a long-lasting solution to eating disorders such as obesity.

Scientists investigated the hypothalamus section of the brain – which regulates sleep and wake cycles, energy expenditure, appetite, thirst, hormone release and many other critical biological functions. The study looked specifically at the nerve cells that regulate appetite.

The researchers used ‘genetic fate mapping’ techniques to make their discovery – a method that tracks the development of stem cells and cells derived from them, at desired time points during the life of an animal.

They established that a population of brain cells called ‘tanycytes’ behave like stem cells and add new neurons to the appetite-regulating circuitry of the mouse brain after birth and into adulthood.

“Unlike dieting, translation of this discovery could eventually offer a permanent solution for tackling obesity,” lead researcher Dr Mohammad K Hajihosseini, said.

To read the complete article…..Click here

An Anti-Obesity Pill

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pillsFrom Your Health Journal…..An interesting article from The Jewish Press by Tzvi Ben-Gedalyahu about an anti-obesity pill. We know how obesity is on the rise all over the world, and obesity related illnesses are also on the rise including heart disease, asthma, cancer, type 2 diabetes, and weak joints. Sedentary lifestyle along with poor eating habits has been a major contribution. Now, an Israeli-made pill may be on its way to make the world slimmer. The “slim pill” to reduce obesity could go on the market as a medicine, with the help of a major pharmaceutical company. The slim-down pill is made from indigestible edible fiber taken before a meal. The pills, after coming in contact with water, inflate and make food more viscous, keeping it in the stomach longer, and creating the sense of being sated. Please visit the Jewish Press web site (link provided below) to read the complete article. It was well written and informative.”

From the article…..

An Israeli-made pill may be on its way to make the world slimmer. The “slim pill” to reduce obesity could go on the market as a medicine, with the help of a major pharmaceutical company.

The Israeli start-up Gelesis is in advanced talks with a large pharmaceutical company to develop its pill that makes people fat people feel their stomachs are full, resulting in less food intake and a loss in weight.

The pharma company was not identified by Israel’s Globes business newspaper, which said that Gelesis soon will publish results of a recent clinical trial of the pill.

Instead of asking the US Food and Drug Administration (FDA) to consider the product as a nutritional supplement or medical device, the Israeli company wants to offer it is a medicine in to increase its market appeal.

The value of the deal with the foreign pharmaceutical company could reach hundreds of millions of dollars. The unidentified company will invest millions of dollars for developing the pill and will pay royalties on sales, Globes added.

The slim-down pill is made from indigestible edible fiber taken before a meal. The pills, after coming in contact with water, inflate and make food more viscous, keeping it in the stomach longer, and creating the sense of being sated.

A study of the pill’s effects several years ago showed a high rate of those who said they felt they had enough to eat, while only 16 percent reported they suffered side effects of discomfort, which Gelesis may be able to reduce by changing the dosage for certain individuals.

To read the complete article…..Click here

Sleeping Pills Can Be Deadly

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By Dr. Michael Murray

pillsWhen you can’t sleep, the temptation to pop a sleeping pill is strong. But did you know you could be risking your life?

There’s a large body of research indicating that sleeping pills may contribute to as many as 500,000 deaths each year in the United States. Most sleeping pills are “sedative hypnotics”— a class of drugs used to treat anxiety. Examples include Xanax, Valium, Lunesta, and Ambien. Most of these drugs are highly addictive and come with a range of side effects, such as dizziness, drowsiness, and impaired coordination.

Sleeping Pills’ Dark Side

The most serious risks of these drugs relate to their effects on memory and behavior. Because they act on brain chemistry, sleeping pills can cause changes in brain function and behavior, including memory impairment, nervousness, confusion, hallucinations, irritability, and aggressiveness. They have also been shown to increase feelings of depression, including suicidal thinking.

Daniel F. Kripke, MD, Professor of Psychiatry Emeritus at the University of California, San Diego, has worked for more than 30 years assessing the risk of sleeping pills, and his findings are stunning.

For one thing, 18 population-based studies have shown a clear link between the use of sleeping pills and increased mortality risk. Four of these studies specifically found that the use of sleeping pills predicted increased risk of death from cancer.

sleepIn Kripke’s latest study, published February 2012 in BMJ Online, his team obtained medical records for 10,529 people prescribed hypnotic sleeping pills, and compared them to records for 23,676 matched patients never prescribed sleeping pills. Over an average of 2½ years, the death rate for those who did not use sleeping pills was 1.2 percent, versus 6.1 percent for those who did. Subjects with sleeping pill prescriptions also had a 35 percent higher risk of cancer. Based on these findings, Kripke estimates that sleeping pills can be linked to 320,000—507,000 US deaths each year.

Poor Sleep Quality

Sleep recharges the energy within our cells and, among other things, helps to remove harmful chemicals from the body—particularly the brain. Sleep also helps enhance antioxidant mechanisms that reduce free radical damage. A likely explanation for the potential negative effects of sleeping pills is that they interfere with these normal sleep patterns, thereby robbing the body of sleep’s powerful healing effects.

Sleeping pills are also notorious for preventing deeper stages of non-REM sleep. That’s usually why these drugs produce a morning “hangover” feeling.

Cause and Effect

Sleep recharges the energy within our cells and, among other things, helps to remove harmful chemicals from the body—particularly the brain.

The first step is to identify and address the causes of the problem. Consider sleep maintenance insomnia, when people are able to fall asleep but awaken in the middle of the night and have difficulty getting back to sleep. Many people with this condition suffer from faulty blood sugar control, so addressing that issue can dramatically improve sleep quality.

Other common causes of insomnia are stress, depression, anxiety, caffeine sensitivity, and even certain medications—there are well over 300 drugs that can interfere with normal sleep.

Natural Sleep Aids

It’s important for people to utilize natural measures to treat insomnia, as doing so avoids the major health consequences associated with sleeping pills.

I recommend a combination of melatonin (3 mg), 5-HTP (30 mg), and L-theanine (200 mg). These ingredients work together to decrease nighttime awakenings and the time required to fall asleep.

Recent studies have also substantiated the herb valerian’s ability to improve sleep quality and relieve insomnia. As a mild sedative, use up to 900 mg, 30-45 minutes before going to bed.

There are lots of free articles about safe, effective, natural alternatives to prescription and over-the-counter medications at my website: www.drmurray.com. And if you sign up for Weekly Fast Facts at the website, you’ll receive a free copy of my book, Stress, Anxiety and Insomnia! What the Drug Companies Won’t Tell You and Your Doctor Doesn’t Know.

– Michael T. Murray ND is a naturopathic physician regarded as one of the world’s top authorities on natural medicine. An educator, lecturer, researcher, and health food industry consultant, he is the author of more than 30 books, including his newest with coauthor Joseph Pizzorno ND, The Encyclopedia of Natural Medicine (Atria, 2012). Learn more at www.DrMurray.com.