SRC-1 Gene Variants Linked To Human Obesity

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From The Baylor College of Medicine…..

BaylorCollegeMaintaining a healthy body weight is no simple matter. A better understanding of how the body regulates appetite could help tip the scale toward the healthy side. Contributing toward this goal, a team led by researchers at Baylor College of Medicine and the University of Cambridge reports in the journal Nature Communications that the gene SRC-1 affects body weight control by regulating the function of neurons in the hypothalamus – the appetite center of the brain.

Mice lacking the SRC-1 gene eat more and become obese. SRC-1 also seems to be involved in regulating human body weight. The researchers identified in severely obese children 15 rare SRC-1 genetic variants that disrupt its function. When mice were genetically engineered to express one of these variants, the animals ate more and gained weight.

“The protein called steroid receptor coactivator-1 (SRC-1) is known to participate in the regulation of body weight, but its precise role is not clear,” said co-corresponding author Dr. Yong Xu, associate professor of pediatrics and of molecular and cellular biology and a researcher at the USDA/ARS Children’s Nutrition Research Center at Baylor College of Medicine and Texas Children’s Hospital. “Here we explored the role of SRC-1 in the hypothalamus, a brain area that regulates appetite.”

The researchers discovered that SRC-1 is highly expressed in the hypothalamus of mice, specifically in neurons that express the Pomc gene. Pomc neurons are known to regulate appetite and body weight.

Further experiments showed that SRC-1 is involved in regulating the expression of Pomc gene in these cells. When Xu and his colleagues deleted the SRC-1 gene in Pomc neurons, the cells expressed less Pomc and the mice ate more and became obese.

The researchers also explored whether SRC-1 also would play a role in regulating human body weight.

“We had identified a group of severely obese children carrying rare genetic variants in the SRC-1 gene,” said co-corresponding author Dr. I. Sadaf Farooqi, professor of metabolism and medicine in the Department of Clinical Biochemistry at the University of Cambridge and Wellcome Trust Principal Research Fellow.

Working together, Xu, Sadaf Farooqi and their colleagues found that many of the SRC-1 variants in the obese children produced dysfunctional proteins that disrupted the normal function of SRC-1. On the other hand, SRC-1 variants in healthy individuals did not disrupt SRC-1 function.

saladheartsmallFurthermore, mice genetically engineered to express one of the human SRC-1 genetic variants found in obese children ate more and gained weight. This is the first report of SRC-1 playing a role in the hypothalamus in the context of body weight control.

“By providing evidence that bridges basic and genetic animal studies and human genetic data, we have made the case that SRC-1 is an important regulator of body weight,” Xu said.

Other contributors to this work include Yongjie Yang, Agatha A. van der Klaauw, Liangru Zhu, Tessa M. Cacciottolo, Yanlin He, Lukas K.J. Stadler, Chunmei Wang, Pingwen Xu, Kenji Saito, Antentor Hinton Jr, Xiaofeng Yan, Julia M. Keogh, Elana Henning, Matthew C. Banton, Audrey E. Hendricks, Elena G. Bochukova, Vanisha Mistry, Katherine L. Lawler, Lan Liao, Jianming Xu, Stephen O’Rahilly, Qingchun Tong, UK10K consortium, Inês Barroso and Bert W. O’Malley. The authors are affiliated with one or more of the following institutions: Baylor College of Medicine; University of Cambridge Metabolic Research Laboratories; Wellcome Trust-MRC Institute of Metabolic Science; Huazhong University of Sciences & Technology, China; Wellcome Sanger Institute, Cambridge; University of Colorado – Denver and University of Texas Health Science Center at Houston.

For a complete list of the sources of financial support for this project, visit this link.


Research Discovers Genes Linked To Twinning And Reproductive Fitness

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This article is provided by the Baylor College of Medicine, please share your comments below…..

mombabyBearing fraternal non-identical twins, or dizygotic (DZ) twinning, has been known to run in families. Studies have suggested that DZ twinning is potentially influenced by more than one gene and linked to a maternal factor. In a study published in the American Journal of Human Genetics, an international collaborative team of researchers reports the finding of two genes that are associated with increased odds for women bearing fraternal twins.

“We know that dizygotic, or non-identical twins, is heritable and passed on down the maternal lineage. We had spent several years first identifying twinning genes in a really spectacular group of new world monkeys, the marmoset, who always have twins or triplets. Now we were ready to tackle the genetics of twinning in humans,” said Dr. Kjersti Aagaard associate professor of obstetrics and gynecology at Baylor College of Medicine and OB/GYN and maternal fetal medicine specialist at Texas Children’s Pavilion for Women, and one of the study’s lead authors. “Working with our colleagues around the globe, we not only found two genes with links to twinning, but to a number of different important signs of reproductive fitness.”

“There’s an enormous interest in twins and in why some women have twins while others don’t,” said Dr. Dorret Boomsma, a biological psychologist at Vrije Universiteit (VU), Amsterdam, and corresponding author for this work, who has compiled one of the largest twin databases in the world. “The question is very simple and our research shows for the first time that we can identify genetic variants [variations of a gene] that contribute to this likelihood.”

The follicle stimulating hormone (FSHB) gene, one of two genes found to be linked to DZ twinning, has shown significant effects on fertility affecting multiple reproductive aspects. For instance, FSHB helps control the menstrual cycle and the production of eggs by the ovary.

“We found that not only did the FSHB gene variant in moms associate with an increased likelihood of having DZ twins, but was associated in a gene dose-dependent manner to the amount of circulating follicle stimulating. In addition, women from four different cohorts around the globe carrying this genetic variant had their first period, menopause, their first child and their last child at an earlier age than women carrying other FSHB genetic variants,” said Aagaard.

Women who carried this FSHB genetic variant also showed signs of less occurrence of polycystic ovarian syndrome. With this discovery, researchers were able to tie this FSHB gene to multiple reproductive fitness traits.

The second gene found by the research team, SMAD3, affected the bearing of dizygotic twins a little differently.

“We found that moms who had this SMAD3 genetic variant also had a higher occurrence of twins,” said Aagaard. “But these moms were older at the birth of their last child, so it is a little bit different than what we saw with the FSHB variant.”

The SMAD3 genetic variant associated with DZ twinning, the authors propose, might increase the chances of DZ twinning by increasing the responsiveness to FSHB through the supporting granulosa cells.

Both genetic variants affect the growth of multiple follicles, which is needed for the development of non-identical twins. Dizygotic twins start with multiple ovulation, a maternal characteristic, and identical twins start with one embryo that splits in half.

This study focused on many different moms of twin cohorts from around the world, including a validation cohort of the population of Iceland. In this group, having each allelic FSHB variant increased women’s chances of having dizygotic twins by 18 percent per allele, and the SMAD3 variant increased the occurrence of twins by 9 percent per allele. Women who had both variants showed an increased chance of 29 percent.

The work has numerous potential applications in reproductive medicine and maternal health. For instance, it may help predict the outcome of multiple births and assist in the development of new strategies to optimize fertility.

Drawing on their recent work in the marmoset, Aagaard is optimistic that these and future evolution based genetic studies focused on twinning may yield key insights for pregnancy and reproductive health.

“What has always struck us about the marmoset is that their capacity for twinning is accompanied by unique adaptive traits that optimize their ability to both carry and care for multiple young at one time,” she said. “The more we can integrate our molecular and genetic findings in both marmoset and human moms, the greater the chance that we can unravel the mysteries of what enables reproductive fitness and optimal pregnancy outcomes in both singleton and multiple gestations.”

For the names, affiliations and support of the authors of this research, visit the Supplementary Materials section of the manuscript.

Vitamin D Linked To Improved Quality Of Life For Those Over 50

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Article courtesy of PRWeb….what are your opinions about Vitamin D injections? Please share your thoughts.

sunDr. Arash Bereliani, the board-certified physician and founder of the IV Therapy Center of Beverly Hills, explains a recent study showing the importance of vitamin D for people over 50.

A recent study published in the journal Quality of Life Research suggests that older patients with higher levels of vitamin D will experience a better quality of life. This quality of life includes more mobility, better ability to perform daily tasks, and less anxiety and depression. The study was conducted by researchers at the University of Alberta’s School of Public Health.

“We’ve known for a long time that vitamin D is vitally important to our bodies,” said Dr. Arash Bereliani, founder of the IV Therapy Center of Beverly Hills. “This study confirms that and goes on to show how important vitamin D is for overall health and happiness, especially in middle-age adults.”

Where Does Vitamin D Come From?

“The majority of our vitamin D intake comes from the sun,” explained Dr. Bereliani. “While it appears naturally in some foods, this typically accounts for a small amount of what we need.”

When the body doesn’t get enough vitamin D a number of subtle but harmful symptoms can result, including cognitive impairment and an increased risk of dying from cardiovascular disease.

Because of this, it is important that patients are aware of the potential for vitamin D deficiency. Common causes of low levels of vitamin D include:

* Not getting enough sunlight, which is especially common in office workers

* Not eating enough foods with vitamin D, such as eggs, fish, and cheese

* Having certain gastrointestinal problems that prevent your body from absorbing vitamin D from food

* Having kidney problems that prevent the body from converting vitamin D

* Obesity

Vitamin D Injections

If you do suffer from a deficiency of vitamin D, the solution might require more than just a day in the sun or changes to your diet.

“Vitamin D injections offer a high-dose, targeted amount of vitamin D that is specially designed to help those who are lacking,” said Dr. Bereliani. “These injections are highly effective for people of all ages, but as you can see from this study, adults over 50 can really benefit.”

In addition to offering vitamin D injections, the IV Therapy Center of Beverly Hills offers a wide range of intravenous vitamins and minerals, including vitamin C, MSM, and glutathione. IV therapy and injections can be used to treat a broad variety of conditions. Some of the most common are fatigue, malabsorption, cold, flu, and certain neurological conditions.

About The IV Therapy Center

The IV Therapy Center is a leading provider of IV vitamin therapy for the prevention and treatment of a broad variety of diseases and conditions. The IV Therapy Center also offers IV treatment designed to improve overall health and well-being. We specialize in administering high-dose Vitamin C, IV glutathione, IV MSM, Myers’ cocktail, IV magnesium therapy, and a number of other injectable therapies in a relaxing, spa-like atmosphere.

To learn more about the IV Therapy Center visit us on the web at

Fact Or Myth: Sleep Apnea Linked To Low Testosterone Levels In Men?

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By Dr. Michael Layton (DDS)

mansmileIs there a link between sleep apnea and low testosterone levels in men? recently posted the connection between the two in their 13 Surprising Facts About Testosterone. How valid is this? Let’s examine the facts and nothing but the facts to determine the implications of sleep apnea on testosterone.

What Is Sleep Apnea?

Lawrence Epstein, M.D. of Harvard Medical School and the editor of Harvard Health Publications special health report defines sleep apnea as “a collapse of the upper airway during sleep that is due to the size of the airway and the changes that happen when you fall asleep. The airway is a flexible tube where air passes through the mouth or nose. When you fall asleep the tissue surrounding the breathing tube narrows a little bit. When it closes halfway thats when you start to get an obstruction to airflow which causes very turbulent airflow, resulting in the tissues to vibrate and thats snoring. When the airway completely closes off thats apnea.”

The closing off the airway triggers the brain of the individual to wake up, sleep apnea sufferers can have their sleep interrupted from 25 to 50 times per hour. Sleep apnea is chronic condition affecting 858,900 Canadians who are 18 years and older. Statistics for people who suffer from this sleep disorder reported being diagnosed with the more serious obstructive sleep apnea (OSA). This more severe form affects 26 percent of Canadians or 1 in four adults. These statistics can be found at the Public Health Agency of Canada from the 2009 Canadian Community Health Survey provisioned through Stats Canada.

Symptoms of Sleep Apnea

mansleepingatdeskSleep apnea is more common in males than in females.

Symptoms are as follows:

● interruption of sleep

● shortness of breath

● loud snoring

● waking up with a dry or sore throat

● headaches

● constant reawakening

● decreased interest in sex

Obstructive sleep apnea (OSA) occurs commonly in people who suffer from obesity, diabetes, heart attacks and strokes, if left untreated it will only exacerbate these preconditions. Extreme fatigue that results from waking up multiple times in a night leads to depression, driving accidents and workplace hazards. When your mother told you to go to bed early when you were a child she may have known a thing or 2 unbeknownst to her about natural health. A good night’s sleep can not be underestimated for your overall health.

What Is Testosterone?

Testosterone is produced in the testes it is the secondary sex characteristic responsible for the reproductive development of the male gender. This male sex hormone is commonly associated with sexual desire and the production of sperm. The three main types of testosterone classification are as follows:

1. Free Testosterone. Total testosterone the purest form found in the human body with no proteins attached to it. This testosterone makes up 2 to 3 percent of total testosterone levels in the human body. Free testosterone is really important for bodybuilders and athletes in sports.

2. SHBG-bound Testosterone. SHBG is bound with the sex hormone globulin. It can not be used to build muscles or change a persons mood. SHBG makes up 40 to 50 percent of our total testosterone levels.

3. Albumin bound Testosterone. Albumin is a protein found in the liver that helps stabilize extracellular fluid in the body. Just like SHBG Albumin is biologically inactive.

Testosterone governs the following factors:

● Skin-Hair growth, balding, sebum production

● Brain-Libido, mood

● Liver-Synthesis of serum proteins

● Male Sexual Growth-penile growth, spermatogenesis, prostate growth and function

● Muscle development-increase in strength and size

● Kidney-stimulation of erythropoietin production

● Bone marrow- stimulation of stem cells

● Bone-accelerated linear growth

manphoneTestosterone affects your level of focus, bone density and last but not least the size of your muscles. Most people associate testosterone with bodybuilders and aggression in athletes especially football players, boxers and MMA fighters. Most of the testosterone in the human body gets bound by the sex hormone binding agent globulin that grabs the testerone preventing its over release, there is another protein amylin also grabs the testerone for when its slowly needed as required. The globulin protein increases as men age leading to decreased levels of testosterone.

Symptoms of Low Testosterone

● erectile disfunction

● lack of sex drive

● lack of focus and ambition

● obesity

● decreased muscle mass

● bone density decrease

● abnormal male breast tissue

● low sperm count

● loss of body hair

● mild anemia

● decreased energy and depression

Low levels of testosterone in men can lead to an increased risk of chronic conditions like diabetes or hypertension or even death in some cases.

Linking Sleep Apnea and Low Testosterone

doctorAny physician out there will acknowledge there is a direct link between aging and a decrease in testosterone levels and higher incidences of sleep apnea. Testosterone deficiency or hypogonadism is prevalent among obese people. If noticed during this article there are many common symptoms related to men who have low levels of testosterone and people who have sleep apnea. All evidence points to a definite correlation for men who have sleep apnea and decreased levels of the male hormone testosterone.

Medical doctors recommend getting blood work done if your energy levels are low or getting a polysomnogram for possible sleep apnea. Low levels of testosterone are linked to low levels of insulin production making people susceptible to Type II Diabetes. Obesity is a common denominator in people who have diabetes. Individuals who are diabetic are at an increased risk for sleep apnea. Medical studies have drawn too many parallels between sleep apnea and low testosterone levels in men for this issue to be ignored.

If you are a male who is experiencing any of the symptoms outlined you many want to consult with your physician on your next checkup.

– Dr. Michael Layton (DDS) is a South Surrey Dentist, based in British Columbia. He has been in the dental industry for the last decade and received his Doctor of Dental Surgery from the University of Washington. He takes pride in providing a positive and caring dental solutions for people of every walk of life. You can follow him on Google+.

Health Benefits Linked To Drinking Tea

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From Your Health Journal….this is an older article, but had some interesting material in it that we thought was beneficial to read about….

teaTea contains substances that have been linked to good health. Regular tea drinkers are less likely to develop diabetes and may have a lower risk of heart disease.

Tea, especially green tea, is often said to be good for your health. Tea contains substances linked to a lower risk for heart disease, cancer, and diabetes. But keep tea’s healthy boost in perspective, says the September 2014 Harvard Men’s Health Watch.

“Tea consumption, especially green tea, may not be the magic bullet, but it can be incorporated in an overall healthy diet with whole grains, fish, fruits and vegetables, and less red and processed meat,” says Qi Sun, assistant professor in the Department of Nutrition at the Harvard School of Public Health.

The main health-promoting substances in tea are polyphenols, in particular catechins and epicatechins. Lab and animal studies say these molecules have anti-inflammatory and antioxidant properties. Harvard-led studies of large groups of people over time have found that tea or coffee drinkers are at lower risk for diabetes and possibly cardiovascular disease. Coffee also contains polyphenols.

Now here’s the key caveat: It remains unclear whether the tea itself is the cause of these benefits and, if so, how it works its magic. The studies attempt to rule out the possibility that tea drinkers simply live healthier lifestyles, but it’s difficult to be sure. That said, tea itself appears to have no harmful effects except for a case of the jitters if you drink too much caffeinated brew. It fits in perfectly well with a heart-healthy lifestyle.

One important warning: A cup of tea contains only a couple calories. Processed, sugar-sweetened tea beverages are loaded with extra calories. “If there are any health benefits to green tea consumption, it’s probably completely offset by adding sugar,” Sun says.

Read the full-length article: “Tea: A cup of good health?”

Also in the September 2014 issue of the Harvard Men’s Health Watch:

* Herbs and supplements for joint support

* Who needs an antiviral booster after catching the flu?

* Tips for choosing a hearing aid

* It’s never too late to boost brain health

The Harvard Men’s Health Watch is available from Harvard Health Publications, the publishing division of Harvard Medical School, for $20 per year. Subscribe at or by calling 877-649-9457 (toll-free).

– Courtesy of PRWeb

Southern Diet Linked To Death In Those With Kidney Disease

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newsEating a Southern-style diet results in higher death rates in those with kidney disease, according to research published in the August issue of the National Kidney Foundation’s American Journal of Kidney Diseases.

“This is the first study to identify a regionally specific diet pattern that is highly associated with adverse outcomes among persons with kidney disease,” said lead author Orlando Gutiérrez, MD, Associate Professor of Medicine at the University of Alabama at Birmingham. “It’s well known that the Southern region has poor health outcomes in a number of different areas including stroke, heart disease and sepsis, and that the style of diet plays a role.”

According to the National Kidney Foundation, modifying lifestyle through healthy diet as well as controlling blood pressure and blood sugar, quitting smoking, regular exercise and maintaining a normal weight, can reduce the risk of kidney disease and related conditions.

Using the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, the research team identified 3,972 participants who had stage 3-5 chronic kidney disease, but had not started dialysis. They then analyzed dietary patterns in those individuals. Those who primarily ate a cuisine of processed and fried foods, organ meats and sweetened beverages, items popular in Southern diets, had a 50% increase in risk of death over a 6.5-year follow-up period.

While many studies have looked at individual nutrients such as sodium or potassium and their effect on longevity in kidney patients, this study focused on dietary patterns.

“People don’t eat nutrients in isolation,” said Thomas Manley, director of scientific activities, National Kidney Foundation. “This study suggests that those caring for people with kidney disease should be focusing on patterns of eating and reducing processed foods and saturated fat, rather than on individual minerals and nutrients. It’s the overall patterns that are strongly associated with adverse outcomes.”

Surprising Results

The same study showed that while a healthy diet alone — comprised primarily of whole foods, fruits and vegetables – was associated with improved survival, it had no protective benefit when it came to progression to kidney failure.

“This doesn’t mean that eating a healthy diet doesn’t help, but it suggests that healthy lifestyle overall — not smoking, exercising and eating right — the combination of these things is more important for kidney health,” Dr. Gutiérrez said.

Kidney Disease Facts from the National Kidney Foundation

· 1 in 3 American adults is at high risk for developing kidney disease today. The risk increases to 1 in 2 over the course of a lifetime.

· High blood pressure, diabetes, a family history of kidney failure and being over 60 are major risk factors for developing kidney disease.

· 1 in 9 American adults has kidney disease — and most don’t know it.

· Early detection and treatment can slow or prevent the progression of kidney disease.

· Kidney disease risk can be reduced by controlling blood pressure and blood sugar, quitting smoking, regular exercise, maintaining a healthy weight, and avoiding excessive use of pain medications.

The National Kidney Foundation (NKF) is the leading organization in the U.S. dedicated to the awareness, prevention and treatment of kidney disease for hundreds of thousands of healthcare professionals, millions of patients and their families, and tens of millions of Americans at risk. For more information, visit

– Submitted by Ellie Schlam of the NKF.

New Study: Severe Obesity Linked To Poor Kidney Function In Teens

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ObesityAlmost 18% of severely obese adolescents show signs of abnormal kidney function, according to new research presented here today at the National Kidney Foundation’s 2014 Spring Clinical Meetings.

The presence of too much albumin–a type of protein–in the urine, known medically as albuminuria or proteinuria, is an early sign of kidney damage. Doctors also use a test called glomerular filtration rate (GFR) to estimate how quickly filtered fluid flows through the kidneys. A GFR of 90 or over indicates normal kidney function, while GFR less than 90 indicate a progressive loss of kidney function. A GFR that’s too high, which is common among obese children and adults, indicates hyperfiltration, meaning the kidneys are working extra hard. Having hyperfiltration for a long period of time can lead to leakage of protein into the urine.

Among 242 adolescents enrolled in the Teen-Longitudinal Assessment of Bariatric Surgery study , 17 percent had protein in their urine, 3 percent had abnormally low GFR (less than 60), and 7 percent had abnormally high GFR (more than 150), Dr. Nianzhou Xiao of Cincinnati Children’s Hospital Medical Center and colleagues found.

Teens with a higher body mass index, as well as those with less sensitivity to the blood-sugar-regulating hormone insulin, were more likely to have abnormally low GFR. Females were more likely than males to have protein in their urine.

“This study represents the first attempt to characterize kidney function status in a large cohort of severely obese adolescents,” Dr. Xiao said. “We plan to continue following them up after bariatric surgery procedures. It will be very important to see whether their kidney function improves after surgical weight loss.”

“Severe obesity is increasing and now affects 4-6% of U.S. children and adolescents. If untreated, obesity during adolescence is associated with a higher prevalence of chronic kidney disease and other serious conditions in adulthood, making obesity a huge public health burden. Pediatricians should counsel obese children and their family proactively about the health concerns linked to obesity and the importance of weight loss for patients who are obese,” said Beth Piraino, MD, President of the National Kidney Foundation.

obeseboyvectorbelly“This study indicates that kidney dysfunction is present in childhood obesity along with such complications as high blood pressure or diabetes,” continued Piraino. “Lifestyle changes such as increased physical activity and healthy eating are critical to improving the overall health of the American population and need to start with our youth. The National Kidney Foundation has developed a number of educational initiatives to promote healthy lifestyle and protect the kidneys.”

The National Kidney Foundation is the leading organization in the U.S. dedicated to the awareness, prevention and treatment of kidney disease for hundreds of thousands of healthcare professionals, millions of patients and their families, and tens of millions of Americans at risk. For more information, visit

– Submitted by Ellie Schlam of The National Kidney Foundation

RadioMD Reveals That High Death Rate For Pancreatic Cancer Linked To Lack Of Effective Screening Methods

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newsThe tragedy of pancreatic cancer is that in 80 percent of cases, it is only diagnosed after it spreads to other parts of the body, which explains why it is the fourth leading cause of death in the U.S. Dr. Madappa Kundranda,PhD, a medical oncologist at Cancer Treatment Centers of America at Western Regional Medical Center, was a guest on’s ‘Managing Cancer” radio show, where he noted that according to the American Cancer Society, the rates of pancreatic cancer have been slowly increasing over the past 10 years, and today it is the 10th most common cancer..

“The danger of pancreatic cancer is that there is not an effective screening method, so by the time we see patients exhibiting signs of this cancer, which includes back ache, fatigue, weight loss and jaundice, it has usually spread to other parts of the body, such as the lymph nodes,” said Dr. Kundranda, .whose main focus is on patients with gastrointestinal cancers, but he also treats a variety of other types of advanced-stage and complex cancers.

Dr. Kundranda noted that pancreatic cancer is diagnosed through blood tests and radiological testing, and if a growth is identified early, it can be resected and the cancer is eliminated. Stage 4 cancers require surgery, radiology and chemotherapy.

“The key to treatment is taking a multi-disciplinary approach, involving professionals in many fields, including therapists and dieticians, who can help enhance the performance of patients in everyday tasks to improve range of movement and reduce pain,” concluded Dr. Kundranda.

The “Managing Cancer” show is hosted by Melanie Cole, MS and can be heard on, and this particular show is in the archive on located here.

ABOUT RadioMD is a “talking” health information source featuring top guests and experts in the world of health and medicine that provide vital health and wellness content in spoken word form. Produced in a talk radio, easy to listen to conversational style, RadioMD shows help listeners understand everyday health issues as well as complex medical conditions. In addition to its variety of live, interactive talk audio features and programming, RadioMD offers an Audio Library of top talk shows on just about every health and wellness, diet & fitness subject.

– Submitted by David Brimm

Endometriosis May Be Linked To Periodontal Disease

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By P., Piero D.D.S.

healthywordsResearch in the last few years has shown that periodontal disease is linked to one’s general health. There are international researchers reporting on these links every day. The latest studies by the University of Michigan Endometriosis Center reported the possibility that there is an association between endometriosis and periodontal disease. Both are immune response deficiencies. In the study, women with endometriosis had a 57% higher chance of having perio issues than those without endometriosis. The study consisted of over 4000 women.

Endometriosis is an concern found in women of childbearing age. Often causing pain, abnormal bleeding and sometimes infertility, it is the thickening of the outside of the uterus. No one knows the actual cause for endometriosis. Depending on age and whether the patient wants to become pregnant determines the treatment plan. Medications such as pain relievers, hormone treatment, oral contraceptives and others are often used. For severe cases or in those treating infertility, surgery is another option.

Periodontal disease is a chronic infectious inflammation found in the mouth. The word comes from “peri” meaning around and “dontal” meaning tooth. Some degree of this disease affects over eighty percent of all adults. Perio infection (affecting soft tissue) and tooth decay (affecting hard tissue) are the most prevalent diseases on the planet earth, however, because it’s in the mouth, out-of-sight, it is often put out-of-mind. Swollen gums, loose teeth, painful chewing and bleeding gums are some of the symptoms. Often there are no outward symptoms. Therefore it is imperative that you see a dentist regularly since they can determine if periodontal disease or gingivitis exists and to what extent.

No one knows for sure the reason for the possible link between periodontal disease and endometriosis.

No one knows for sure the reason for the possible link between periodontal disease and endometriosis. The researchers at University of Michigan concluded, “Although it is conceivable that the multifactorial development of endometriosis may be augmented by an immune response to an infectious agent, the potential underlying link between endometriosis and periodontal disease may be a generalized, global immune dysregulation.” References: (

Like most studies, this one was not conclusive but does indicate that perio disease affects the whole body, not just the mouth. Women should visit a dentist every three months and if periodontal disease is present, should undergo treatment immediately. Finally, impeccable home oral care is necessary to keep teeth and gums healthy.

– Dr. Piero, a Holland, MI dentist for over thirty years, is the inventor of Dental Air Force®. Articles published are on periodontal health related to heart disease, respiratory health, diabetes, strokes, and other systemic diseases. He is the Executive Editor for Journal of Experimental Dental Science, a contributing author to Hospital Infection Control: Clinical Guidelines and soon-to-be published book, Put Your Money Where Your Mouth Is.

Former Swim Star Susie O’Neill Warns Childhood Obesity Could Put Olympic Future In Peril

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basketballvectorFrom Your Health Journal…..”I always like to promote from Australia, as I always enjoy their health articles, many of them aimed at fighting childhood obesity. Today’s article review is called Former Swim Star Susie O’Neill Warns Childhood Obesity Could Put Olympic Future In Peril written by Rosie Squires of the News Limited Network. So many Olympic athletes are very supportive in the fight against childhood obesity. Who better to speak on this then someone who has trained their whole lives to be the best at one sport, someone who is very disciplined in their trade. Susie O’Neill, an Olympic gold medalist is speaking out about the childhood obesity epidemic not only facing the youth of the world, but her home country. She fears we may one day be unable to field an Olympic team at all. Suzie feels that the current crop of young kids simply didn’t have the same drive to play sport and keep active as her generation did. She may be right, as the current generation of children are the technology generation, where they play on their computers, Ipads, or video games, rather than play outside with physical activity. Obesity is on the rise all over the world, and many children suffer from chronic illness due to obesity such as heart disease, cancer, weak joints, and type 2 diabetes. Not to mention, many of these same children get bullied at school and have low self esteem. So, please visit the web site and read this interesting article. The link is provided below.”

From the article…..

She’s one of our greatest swimmers but Susie O’Neill is so concerned about the health and fitness of our children she fears we may one day be unable to field an Olympic team at all.

The dual gold medallist, known affectionately as Madame Butterfly by an adoring nation, said the current crop of young kids simply didn’t have the same drive to play sport and keep active as her generation did.

“It is a concern. If you imagine a pyramid, the elite person is the top of the pyramid, and that person is higher if you have a bigger base – so the more kids you have doing sport, and competing for the top, the higher that top athlete is,” the mother-of-two told News Limited. “We need that big base to draw kids from.”

O’Neill pointed to the poor performance of our swim team at the 2012 London Olympics, where they brought home only one gold medal, to issue a grim warning for sports fans.

“Look at what happened to the Olympic team last year,” she said.

“Will we even have an Olympic team in the future?”

O’Neill expressed her fears as she launched a nationwide health campaign with the Australian Food and Grocery Council called Together Counts.

The campaign aims to teach Australians how to balance diet and exercise via a website, which offers meal suggestions, lunchbox ideas and physical activity tips for the family.

O’Neill, 39, said Australians needed to start taking responsibility for their fitness.

“I was shocked to learn that one in four children are overweight or obese,” she said.

“I think families need to be taking more responsibility. We need to be doing exercise as a family and eating nutritious meals.”

To read the complete article…..Click here