New Drug Found To Cure Rheumatoid Arthritis

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newsBeverly Hills rheumatologist Dr. Susan Baker comments on a new drug trial that could revolutionize treatment of Rheumatoid Arthritis for patients.

The findings from a promising drug study for treatment of Rheumatoid Arthritis in mice is set for human trials this year. Published in Proceedings of the National Academy of Sciences (PNAS), the researchers, lead by Teresa Hemmerle of the federal technology institute ETH Zurich in Switzerland, discovered a compound that cleared the affected mice of their symptoms.

Using one of the body’s own immune cells, interleukin 4 (IL-4), and fusing it with an antibody found in certain disease specific inflamed tissue and tumors, the researchers found that the combination of the two elements used together completely eradicated the arthritis induced swelling and inflammation in the toes and paws of the affected mice within days.

“The implications for human uses of this study are very exciting,” said Dr. Susan A. Baker, a rheumatologist in Beverly Hills. “The treatment for Rheumatoid arthritis up to this point has mainly focused on managing pain and slowing long term joint damage and deterioration for as long as possible. The potential for a drug with curative effects would be a watershed moment in the treatment of Rheumatoid Arthritis.”

Rheumatoid Arthritis, an autoimmune disorder that causes painful swelling and inflammation in the joints and can lead to long term joint damage and deterioration currently does not have a cure. While the trajectory between human trials and the availability of a cure can be long and complicated, the researchers are very hopeful that their findings will lead to a viable treatment option for humans down the line.

“Any research or new information that can enhance our treatment options for patients is always a welcome addition,” added Dr. Baker.

The researchers found that when used separately, the components worked to slow the progression of the RA symptoms in the mice, but it was the combination of the two that produced the breakthrough results.

Board certified in both internal medicine and rheumatology, Dr. Baker has been practicing medicine in Beverly Hills since 2003. In addition to her primary practice, she holds teaching position at Cedars Sinai Hospital. and is a clinical instructor of medicine for UCLA, David Geffen School of Medicine. Dr. Baker has been recieved numerous awards including the “Patient’s Choice Award” and the “Most Compassionate Doctor” award.

To contact Susan A. Baker MD, Rheumatology & Internal Medicine please visit, or call (310) 274–7770.

Guest Post – Philip Tucker, Link Found Between Diabetes And Nations that Consume High Fructose Corn Syrup

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diabetesglucoseThe US Center for Disease Control recently released a report detailing the dramatic rise in the prevalence of diabetes in the United States, showing that the number of people who have diabetes across the nation has almost doubled since 1995. This shocking escalation shows no sign of stopping, and if the trend continues then the outlook for our general health is bleak. What is causing the prevalence of diabetes to skyrocket? Why the increase in the number of diagnoses? A second study entitled ‘High fructose corn syrup and diabetes prevalence: A global perspective’ might offer some answers.

This new study examined from a global and ecological perspective the prevalence of type 2 diabetes and the availability of high fructose corn syrup. Forty three countries were examined, and found that diabetes was 20% higher in nations that had higher availability to high fructose corn syrup, even after adjustments were made country-level estimates of body mass indexes, population, and gross domestic product. Their conclusion was that countries with readily accessible HFCS had a higher incidence rate of type 2 diabetes, regardless of obesity.

Of the 43 countries, the United States was ranked at the top, consuming 24.78 kg of HFCS per year, which was nearly double that of Hungary, the second ranking country, which consumed only 16.85 kg. The rate dropped precipitously from there, with Slovakia in third consuming only 9.82 kg. The US also had the highest average BMI at 27.99.

Forty three countries were examined, and found that diabetes was 20% higher in nations that had higher availability to high fructose corn syrup, even after adjustments were made country-level estimates of body mass indexes, population, and gross domestic product.

What is it about HFSC that might cause this increase in diabetes prevalence? An increasing number of studies (such as Stanhope et al. 2009) have found that fructose can have a negative effect on your health. Fructose is always absorbed by your liver, and is metabolized in a way that does not cause an insulin reaction. This results in a lack of insulin to transport the metabolized fructose has been theorized to be a direct cause of weight gain and development of diabetes.

This report was met with scorn by the Corn Refiners Association, who pointed out that correlation does not mean causation. They have issued a statement calling the report “misleading” and “flawed”, and that “uses a severely flawed statistical methodology and ignores well established medical facts to ‘suggest’ a unique link between high fructose corn syrup and Type 2 diabetes.” Audrae Erickson, the president of the association said that, “just because an ingredient is available in a nation’s diet does not mean that it is uniquely the cause of a disease.”

– Phil Tucker is a health and fitness blogger who is looking to grow younger as he gets older. Click here to learn more, or visit his blog!